Dit zijn de beste spelers van de Major League Soccer in FIFA 16 en FIFA 16 Ultimate Team. 

20. Nick Rimando - Real Salt Lake

19. Pedro Morales - Vancouver Whitecaps FC

18. Osvaldo Alonso - Seattle Sounders FC

17. Ignacio Piatti - Impact de Montréal

16. Jermaine Jones - New England Revolution

15. Diego Valeri - Portland Timbers

14. Federico Higuaín - Columbus Crew SC

13. Giovani dos Santos - LA Galaxy

12. Obafemi Martins - Seattle Sounders FC

11. Frank Lampard - New York City FC

10. Michael Bradley - Toronto FC

9. Andoni Iraola - New York City FC

8. David Villa - New York City FC

7. Robbie Keane - LA Galaxy

6. Didier Drogba - Impact de Montréal

5. Clint Dempsey - Seattle Sounders FC

4. Kaká - Orlando City SC

3. Sebastian Giovinco - Toronto FC

2. Andrea Pirlo - New York City FC

1. Steven Gerrard - LA Galaxy